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The above information is for your reference only. It cannot be used in place of a consultation with a medical professional nor as a basis of self-diagnosis or for treatment decision. Only your physician can provide you with accurate diagnosis and appropriate treatment.

Clinical Efficacy in Stroke Patients

Somazina  improves overall recovery

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Data analysis of a total of 1,372 patients with moderate-to-severe acute stroke from 4 clinical trials showed that treatment with oral citicoline within the first 24 hours after symptom onset increased the chance of complete recovery at 3 months  .

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Long-term Somazina prevents decline in cognitive function

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Researchers observed that citicoline treatment for 2 years after the first stroke improved overall cognitive function in a clinical trial involving 163 patients  .

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Cognitive functions evaluated  :

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•    Attention, executive function
•    Language
•    Memory
•    Spatial perception
•    Dexterity
•    Orientation to time

Somazina helps patients regain their independence

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Data analysis of a total of 4,420 patients with acute stroke from 10 clinical trials demonstrated that treatment with citicoline was associated with an increased rate of patient independence  .

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Somazina  has been clinically studied to treat cognitive and neurological disorders associated with stroke.

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References   
1. Warach S, Pettigrew LC, Dashe JF, et al. Effect of citicoline on ischemic lesions as measured by diffusion-weighted magnetic resonance imaging. Ann Neurol 2000;48:713-722.  2. Dávalos A, Castillo J, Álvarez-Sabín J, et al. Oral citicoline in acute ischemic stroke: An individual patient data pooling analysis of clinical trials. Stroke 2002;33:2850-2857.  3. Álvarez-Sabín J, Santamarina E, Maisterra O, et al. Long-term treatment with citicoline prevents cognitive decline and predicts a better quality of life after a first ischemic stroke. Int J Mol. Sci 2016;17:390.  4. Álvarez-Sabín J, Ortega G, Jacas C, et al. Long-term treatment with citicoline may improve poststroke vascular cognitive impairment. Cerebrovasc Dis 2013;35:146-154.  5. Secades JJ, Álvarez-Sabín J, Castillo J, et al. Citicoline for acute ischemic stroke: A systematic review and formal meta-analysis of randomized, double-blind, and placebo-controlled trials. J Stroke Cerebrovasc Dis 2016;25:1984-1996.

Somazina  reduces the volume of stroke-damaged brain tissue

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Researchers observed that oral citicoline helped reduce the volume of brain tissue that had been damaged through acute stroke in a clinical trial involving 81 patients .

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